Spoiler for Slightly NSFW:
Original creator (manga) : Hideaki Yoshikawa
Plot summary : The "science trouble" romantic comedy follows a blonde-haired cyborg girl and a purple-haired half-dog girl who go to extremes with the power of science.
Note : The manga just launched in late 2010, and Akita Shoten published the second compiled volume last month.
It was announced to be a OVA bundled with the third manga volume.
Update : Cast announced : Ryota Ohsaka, Toa Yukimura, Ringo Aoba, Ryō Kasumi, Rino Kawashima, and Yuana Miyazawa. Given the risqué nature of the material, these names are not necessarily the cast members' actual names.